INT25464
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
To our knowledge, the association between hydrocephalus and postoperative spinal adhesive arachnoiditis (SAA) has never been reported. | |||||||||||||||
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The SAA1-alpha/alpha genotype was associated with an increased risk of amyloidosis. | |||||||||||||||
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Variations in plasma sulfur amino acid (SAA) pools are associated with disease risks, but little information is available about the factors affecting plasma SAA pools. | |||||||||||||||
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The results suggest a need to evaluate possible effects of APAP in association with SAA insufficiency as a contributing factor in disease risk. | |||||||||||||||
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Serum concentrations of C-reactive protein (CRP) and serum amyloid A (SAA) were substantially elevated in patients with fever (Table 2 and Additional File 2, Figure S1) which is typical for the syndrome. | |||||||||||||||
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The determination of CRP and SAA was performed by means of immunonephelometry with the Behring Nephelometer Analyzer II (BNII). | |||||||||||||||
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It has been speculated that the interaction between the SAA1 protein and the putative receptor SELS [6] could be involved in the development of insulin resistance, and a recent study in rats showed that the expression level of SELS in liver was higher in diabetic rats compared with both healthy rats and diabetic rats treated with the insulin sensitizer rosiglitazone [25]. | |||||||||||||||
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By 1.2 hours after ingestion of a 200 mg dose, the maximum serum concentration (Cmax) averaged 15.9 micrograms/ml, with more than 99% of the drug bound to serum protein. | |||||||||||||||
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In addition, diclofenac is known to be highly bound to serum protein (>99.7%).[31] Therefore it is likely that diclofenac, at least after administration of a common single dose, does not achieve serum levels fast enough and high enough to inhibit codeine glucuronidation in vivo. | |||||||||||||||
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In contrast to Serum 6, Serum 1 shows strong binding to the pinceau (green arrows in D) colocalizing with Lgi1 (insets in D show the pinceau at higher magnification). | |||||||||||||||
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In contrast, Serum 1 (B) binds to the mf more than the rad, colocalizing with Lgi1. | |||||||||||||||
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MBL2 is a calcium-dependent serum protein that plays a role in the innate immune response by binding to carbohydrates on the surface of a wide range of pathogens including viruses, bacteria, fungi, and protozoa where it can activate the complement system or act directly as an opsonin [17,18]. | |||||||||||||||
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General Comments
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