INT25466

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Context Info
Confidence 0.00
First Reported 1989
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 2.23
Pain Relevance 3.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Rab38) vesicle-mediated transport (Rab38) Golgi apparatus (Rab38)
endoplasmic reticulum (Rab38) GTPase activity (Rab38) cytoplasm (Rab38)
Anatomy Link Frequency
coronary artery 1
brain 1
band 1
amygdala 1
Rab38 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Angina 7 98.88 Very High Very High Very High
amygdala 6 98.60 Very High Very High Very High
cocaine 45 98.32 Very High Very High Very High
withdrawal 9 96.60 Very High Very High Very High
Kappa opioid receptor 6 88.76 High High
ischemia 5 88.04 High High
Opioid 6 72.40 Quite High
addiction 3 64.28 Quite High
anticonvulsant 5 50.00 Quite Low
Pyramidal cell 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coronary Stenosis 1 100.00 Very High Very High Very High
Cv General 3 Under Development 10 98.88 Very High Very High Very High
Diabetic Macular Edema 26 98.60 Very High Very High Very High
Adhesions 11 97.96 Very High Very High Very High
Coronary Artery Disease 3 88.04 High High
Retina Disease 6 86.96 High High
Myocardial Infarction 3 85.32 High High
Diabetes Mellitus 17 83.72 Quite High
Stress 5 77.64 Quite High
Diabetic Retinopathy 9 71.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Good correlation was recognized between grade of coronary artery stenosis, severity score (Sv-S) and rW-R in 28 patients with effort angina pectoris (EAP).
rW-R Binding (recognized) of in coronary artery associated with coronary stenosis and angina
1) Confidence 0.00 Published 1989 Journal Kaku Igaku Section Abstract Doc Link 2526266 Disease Relevance 1.13 Pain Relevance 0.70
A significant increase in [3H]CI-977 binding to KOP-r was detected in the septum of rats treated with an escalating dose binge cocaine administration paradigm and killed 30 min after the last cocaine injection.
KOP-r Binding (binding) of associated with cocaine
2) Confidence 0.41 Published 2007 Journal Synapse Section Abstract Doc Link 17621646 Disease Relevance 0.06 Pain Relevance 0.98
The observed lowering in KOP-r binding, which was shown in two brain regions of cocaine withdrawn animals, might contribute to the persistent dysphoria reported a long time after the discontinuation of the drug.
KOP-r Binding (binding) of in brain associated with cocaine
3) Confidence 0.31 Published 2007 Journal Synapse Section Abstract Doc Link 17621646 Disease Relevance 0 Pain Relevance 0.62
In contrast, there was a decrease in KOP-r binding in the septum and the basolateral amygdala of rats withdrawn for 14 days from chronic escalating dose binge cocaine administration, compared to rats at the end of 14 days chronic escalating dose cocaine administration.
KOP-r Binding (binding) of in amygdala associated with amygdala and cocaine
4) Confidence 0.31 Published 2007 Journal Synapse Section Abstract Doc Link 17621646 Disease Relevance 0.06 Pain Relevance 0.99
Recent studies have revealed that small GTP-binding protein Rho and its target protein ROCK are implicated in the important physiological roles such as cell adhesion and migration mediated through MLC phosphorylation [19, 24].
small GTP-binding protein Rho Binding (implicated) of associated with adhesions
5) Confidence 0.07 Published 2010 Journal Journal of Ophthalmology Section Body Doc Link PMC2905943 Disease Relevance 0.98 Pain Relevance 0
Multiunit activity, revealed after band-pass filtering, was associated with SPW-R events (Fig. 1C-4).
SPW-R Binding (associated) of in band
6) Confidence 0.03 Published 2007 Journal BMC Neurosci Section Body Doc Link PMC1950312 Disease Relevance 0 Pain Relevance 0

General Comments

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