INT254674

Context Info Confidence 0.34 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.51 Pain Relevance 0

cytosol (Map2k2) kinase activity (Map2k2)

Anatomy Link Frequency HT-29 2 Map2k2 (Mus musculus)

Pain Link Frequency Relevance Heat metalloproteinase 7 5.00 Perioperative pain 1 5.00 isoflurane 1 5.00

Disease Link Frequency Relevance Heat Colon Cancer 45 93.28 Targeted Disruption 4 75.60 Adenocarcinoma 8 70.32 Cancer 36 5.00 Metastasis 10 5.00 Intestinal Cancer 8 5.00 Apoptosis 8 5.00 Infection 7 5.00 Carcinoma 4 5.00 Hyperplasia 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

However, the single inactivation of MEK2 was still capable of abolishing the proliferation of HT-29 cells even in the presence of high MEK1 levels.

Negative_regulation (abolishing) of Positive_regulation (inactivation) of MEK2 in HT-29

1) Confidence 0.34 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2596176 Disease Relevance 0.51 Pain Relevance 0

General Comments

This test has worked.