INT254675

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Context Info
Confidence 0.36
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.85
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Map2k2) kinase activity (Map2k2)
Map2k2 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 14 97.36 Very High Very High Very High
Perioperative pain 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 16 98.80 Very High Very High Very High
Cancer 72 90.56 High High
Colon Cancer 90 86.48 High High
Intestinal Cancer 16 57.32 Quite High
Adhesions 4 48.92 Quite Low
Death 4 47.80 Quite Low
Metastasis 20 44.08 Quite Low
Injury 2 11.16 Low Low
Adenocarcinoma 16 5.00 Very Low Very Low Very Low
Infection 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, activation of either MEK1 or MEK2 markedly up-regulated the expression of MMP-13 protein (Fig. 4A).
Regulation (regulated) of Positive_regulation (activation) of MEK2
1) Confidence 0.36 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2596176 Disease Relevance 0.20 Pain Relevance 0.20
MEK1 or MEK2 activation had no significant effect on the expression of the pro-apoptotic proteins Bax and Bak in these cells (data not shown).


Neg (no) Regulation (effect) of Positive_regulation (activation) of MEK2 associated with apoptosis
2) Confidence 0.36 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2596176 Disease Relevance 0.66 Pain Relevance 0

General Comments

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