INT254683

Context Info Confidence 0.01 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.07 Pain Relevance 0.18

plasma membrane (Map2k1, Plaur) kinase activity (Map2k1, Plaur) Golgi apparatus (Map2k1) enzyme binding (Plaur) cytoplasm (Map2k1) cytosol (Map2k1)

Map2k1 (Mus musculus) Plaur (Mus musculus)

Pain Link Frequency Relevance Heat metalloproteinase 7 97.44 Perioperative pain 1 5.00 isoflurane 1 5.00

Disease Link Frequency Relevance Heat Cancer 36 71.44 Intestinal Cancer 8 38.20 Metastasis 10 30.08 Death 2 10.48 Adhesions 2 8.48 Colon Cancer 45 5.00 Adenocarcinoma 8 5.00 Apoptosis 8 5.00 Infection 7 5.00 Carcinoma 4 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Quantitative PCR analysis confirmed that constitutive activation of MEK1 or MEK2 induces the expression of urokinase receptor mRNA (Fig. 4B).

Positive_regulation (activation) of MEK1 Positive_regulation (induces) of Gene_expression (expression) of urokinase receptor mRNA

1) Confidence 0.01 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2596176 Disease Relevance 0.07 Pain Relevance 0.18

General Comments

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