INT254701

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.67
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 2.50
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (CDH1) cell adhesion (CDH1) Golgi apparatus (CDH1)
plasma membrane (CDH1) cytoplasm (CDH1)
Anatomy Link Frequency
plasma 1
CDH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 27 92.00 High High
fibrosis 2 48.56 Quite Low
Inflammation 14 5.00 Very Low Very Low Very Low
rheumatoid arthritis 10 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 15 96.04 Very High Very High Very High
Carcinoma 15 89.32 High High
Repression 6 83.40 Quite High
Aggression 2 81.72 Quite High
Cancer 227 81.12 Quite High
Malignant Neoplastic Disease 5 76.24 Quite High
Disease 15 72.72 Quite High
Recurrence 6 69.32 Quite High
Colon Cancer 77 65.84 Quite High
Pathologic Processes 2 53.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Table 1 shows the percent identity of the human cadherin-11 and E-cadherin transcripts and 3?
Transcription (transcripts) of E-cadherin
1) Confidence 0.67 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2650783 Disease Relevance 0.16 Pain Relevance 0
Table 1 shows the percent identity of the human cadherin-11 and E-cadherin transcripts and 3?
Transcription (identity) of E-cadherin
2) Confidence 0.67 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2650783 Disease Relevance 0.16 Pain Relevance 0
The main hallmark of this process is the loss of E-cadherin expression mainly caused by repressed transcription of this gene (CDH1) [2].
Transcription (transcription) of CDH1
3) Confidence 0.54 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2680015 Disease Relevance 0.81 Pain Relevance 0
Expression of several transcriptional repressors has been shown to down-regulate CDH1 transcription [3].
Transcription (transcription) of CDH1
4) Confidence 0.40 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2680015 Disease Relevance 0.86 Pain Relevance 0
Ectopic expression of MEK1DD or MEK2DD resulted in the loss of E-cadherin staining at the plasma membrane (Fig. 1E), concomitant with a marked reduction of E-cadherin protein and mRNA levels (Fig. 1F and 1G).
Transcription (levels) of E-cadherin in plasma
5) Confidence 0.06 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2596176 Disease Relevance 0.14 Pain Relevance 0
No differences were seen between SW1990 and si-SW1990 with regard to mRNA expression of E-Cadherin, Snail, ZO-1, ZO-2, MMPs and integrins, whereas mRNA expression levels of ?
Transcription (expression) of E-Cadherin
6) Confidence 0.04 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2893453 Disease Relevance 0.38 Pain Relevance 0.17

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox