INT254707

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.67
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Map2k1, BAK1) mitochondrion (BAK1) aging (BAK1)
endoplasmic reticulum (BAK1) Golgi apparatus (Map2k1) intracellular (BAK1)
Map2k1 (Mus musculus)
BAK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 7 5.00 Very Low Very Low Very Low
Perioperative pain 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 8 100.00 Very High Very High Very High
Colon Cancer 45 91.28 High High
Adhesions 2 49.24 Quite Low
Death 2 48.12 Quite Low
Metastasis 10 44.40 Quite Low
Cancer 36 37.44 Quite Low
Adenocarcinoma 8 5.00 Very Low Very Low Very Low
Intestinal Cancer 8 5.00 Very Low Very Low Very Low
Infection 7 5.00 Very Low Very Low Very Low
Carcinoma 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MEK1 or MEK2 activation had no significant effect on the expression of the pro-apoptotic proteins Bax and Bak in these cells (data not shown).


Positive_regulation (activation) of MEK1 Neg (no) Regulation (effect) of Gene_expression (expression) of Bak associated with apoptosis
1) Confidence 0.05 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2596176 Disease Relevance 0.67 Pain Relevance 0

General Comments

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