INT254768

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.05
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Apoe) aging (Apoe) Golgi apparatus (Apoe)
DNA binding (DNMT1) lipid metabolic process (Apoe) cytoplasm (Apoe)
DNMT1 (Homo sapiens)
Apoe (Mus musculus)
Pain Link Frequency Relevance Heat
dexamethasone 92 99.90 Very High Very High Very High
withdrawal 10 5.00 Very Low Very Low Very Low
corticosteroid 4 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 4 50.72 Quite High
Necrosis 2 37.12 Quite Low
Cancer 2 36.76 Quite Low
Obesity 24 28.00 Quite Low
Disease 56 5.00 Very Low Very Low Very Low
Atherosclerosis 12 5.00 Very Low Very Low Very Low
Hyperlipidemia 10 5.00 Very Low Very Low Very Low
Cognitive Disorder 8 5.00 Very Low Very Low Very Low
Graft Vs Host Disease 4 5.00 Very Low Very Low Very Low
Diabetes Mellitus 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, Dex and AIM induced high and robust expression of ApoE, which persisted until the end of the experiment at 21 days.
AIM Positive_regulation (induced) of Gene_expression (expression) of ApoE associated with dexamethasone
1) Confidence 0.02 Published 2008 Journal BMC Biotechnol Section Body Doc Link PMC2596794 Disease Relevance 0 Pain Relevance 0.25
To confirm that Dex was solely responsible for the induction of ApoE secretion, we tested whether the two additional components of AIM induced ApoE expression.
AIM Spec (whether) Positive_regulation (induced) of Gene_expression (expression) of ApoE associated with dexamethasone
2) Confidence 0.01 Published 2008 Journal BMC Biotechnol Section Body Doc Link PMC2596794 Disease Relevance 0.05 Pain Relevance 0.24

General Comments

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