INT254769

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (LDLR, Apoe) lipid metabolic process (LDLR, Apoe) aging (Apoe)
small molecule metabolic process (LDLR) Golgi apparatus (Apoe) cytoplasm (Apoe)
Anatomy Link Frequency
macrophages 1
hepatocytes 1
astrocytes 1
LDLR (Homo sapiens)
Apoe (Mus musculus)
Pain Link Frequency Relevance Heat
dexamethasone 184 81.28 Quite High
cytokine 4 70.32 Quite High
corticosteroid 8 33.84 Quite Low
Inflammation 4 12.04 Low Low
withdrawal 20 5.00 Very Low Very Low Very Low
agonist 8 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Multiple sclerosis 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 112 44.68 Quite Low
Hyperlipidemia 20 24.64 Low Low
Atherosclerosis 24 20.56 Low Low
Stroke 8 17.52 Low Low
INFLAMMATION 4 12.04 Low Low
Injury 4 11.36 Low Low
Atherosclerotic Plaque 4 7.40 Low Low
Obesity 48 5.00 Very Low Very Low Very Low
Cognitive Disorder 16 5.00 Very Low Very Low Very Low
Graft Vs Host Disease 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ApoE also binds to the LDL receptor and facilitates internalization by hepatocytes, macrophages and astrocytes.
LDL receptor Binding (binds) of ApoE in astrocytes
1) Confidence 0.03 Published 2008 Journal BMC Biotechnol Section Body Doc Link PMC2596794 Disease Relevance 0 Pain Relevance 0.07
Since the physiological role of ApoE is dependent binding of lipid and the LDL-receptor, these data suggest that the ApoE would satisfy its role in vivo.
LDL-receptor Binding (binding) of ApoE
2) Confidence 0.02 Published 2008 Journal BMC Biotechnol Section Body Doc Link PMC2596794 Disease Relevance 0 Pain Relevance 0.08
ApoE also binds to the LDL receptor and facilitates internalization by hepatocytes, macrophages and astrocytes.
LDL receptor Binding (binds) of ApoE in hepatocytes
3) Confidence 0.01 Published 2008 Journal BMC Biotechnol Section Body Doc Link PMC2596794 Disease Relevance 0 Pain Relevance 0.07
ApoE also binds to the LDL receptor and facilitates internalization by hepatocytes, macrophages and astrocytes.
LDL receptor Binding (binds) of ApoE in macrophages
4) Confidence 0.01 Published 2008 Journal BMC Biotechnol Section Body Doc Link PMC2596794 Disease Relevance 0 Pain Relevance 0.07

General Comments

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