INT255023

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Context Info
Confidence 0.35
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (DPP4, GIP) small molecule metabolic process (GIP) Golgi apparatus (DPP4)
endoplasmic reticulum (DPP4) cytoplasm (GIP) peptidase activity (DPP4)
DPP4 (Homo sapiens)
GIP (Homo sapiens)
Pain Link Frequency Relevance Heat
adenocard 1 24.96 Low Low
tolerance 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 57 96.92 Very High Very High Very High
Hyperinsulinism 1 88.60 High High
Hypoglycemia 16 85.44 High High
Obesity 3 9.20 Low Low
Body Weight 7 5.00 Very Low Very Low Very Low
Disease 7 5.00 Very Low Very Low Very Low
Renal Disease 6 5.00 Very Low Very Low Very Low
Weight Gain 6 5.00 Very Low Very Low Very Low
Insulin Resistance 6 5.00 Very Low Very Low Very Low
Hyperglycemia 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
GIP levels are also increased via DPP-4 inhibition – the clinical significance of this is unclear, though, as individuals with type 2 diabetes appear to have decreased responsiveness to this incretin (Ahren 2007).
Negative_regulation (inhibition) of DPP-4 Positive_regulation (increased) of GIP associated with diabetes mellitus
1) Confidence 0.35 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2597758 Disease Relevance 0.27 Pain Relevance 0

General Comments

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