INT255043

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Context Info
Confidence 0.35
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.32
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (DPP4, GLP1R) small molecule metabolic process (GLP1R) Golgi apparatus (DPP4)
endoplasmic reticulum (DPP4) signal transducer activity (GLP1R) peptidase activity (DPP4)
DPP4 (Homo sapiens)
GLP1R (Homo sapiens)
Pain Link Frequency Relevance Heat
potassium channel 2 32.52 Quite Low
adenocard 2 25.32 Quite Low
Neuropeptide 4 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 57 96.48 Very High Very High Very High
Hypoglycemia 4 83.52 Quite High
Apoptosis 1 71.96 Quite High
Obesity 5 48.32 Quite Low
Disease 6 5.00 Very Low Very Low Very Low
Hyperglycemia 5 5.00 Very Low Very Low Very Low
Infection 5 5.00 Very Low Very Low Very Low
Insulin Resistance 5 5.00 Very Low Very Low Very Low
Body Weight 4 5.00 Very Low Very Low Very Low
Cardiovascular Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both GLP-1 and GIP are inactivated by DPP-4 resulting in a short half life, which is 1 to 2 min for GLP-1 and 5 to 7 min for GIP (Deacon 2005).
DPP-4 Positive_regulation (inactivated) of GLP-1
1) Confidence 0.35 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2597770 Disease Relevance 0.32 Pain Relevance 0

General Comments

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