INT255075

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Context Info
Confidence 0.36
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.64
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (GLP1R) plasma membrane (GLP1R) signal transducer activity (GLP1R)
GLP1R (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 24 51.80 Quite High
Central nervous system 2 51.20 Quite High
Neuropeptide 4 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
potassium channel 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
nud 1 5.00 Very Low Very Low Very Low
substance P 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 99 98.32 Very High Very High Very High
Hypoglycemia 13 41.72 Quite Low
Body Weight 11 39.44 Quite Low
Apoptosis 1 30.16 Quite Low
Disease Progression 5 21.40 Low Low
Weight Loss 8 9.56 Low Low
Obesity 9 6.52 Low Low
Vomiting 10 5.00 Very Low Very Low Very Low
Disease 9 5.00 Very Low Very Low Very Low
Hyperglycemia 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Conversely, hyperglycaemia acutely reduces the postprandial levels of GIP and GLP-1, possibly through a deceleration of gastric emptying.
Negative_regulation (reduces) of Gene_expression (levels) of GLP-1
1) Confidence 0.36 Published 2010 Journal Pediatr Nephrol Section Body Doc Link PMC2874027 Disease Relevance 0.51 Pain Relevance 0.05
DPP-4 inhibition increases not only prandial but also fasting levels of active GLP-1 and results in an overall increase in GLP-1 levels with maintenance of circadian rhythm throughout the day.
Negative_regulation (fasting) of Gene_expression (levels) of GLP-1
2) Confidence 0.27 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2597770 Disease Relevance 0.13 Pain Relevance 0

General Comments

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