INT255108

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Context Info
Confidence 0.36
First Reported 2008
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.18
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA binding (Celf1) mRNA processing (Celf1) RNA binding (Celf1)
nucleus (Celf1) cytoplasm (Celf1)
Celf1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 4 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
spastic colon 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 56 66.56 Quite High
Myotonic Dystrophy 44 50.00 Quite Low
Disease 29 50.00 Quite Low
Toxicity 42 39.24 Quite Low
Congenital Anomalies 31 6.12 Low Low
Myotonia 28 5.00 Very Low Very Low Very Low
Frailty 17 5.00 Very Low Very Low Very Low
Cataract 15 5.00 Very Low Very Low Very Low
Arrhythmias 2 Under Development 12 5.00 Very Low Very Low Very Low
Aging 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Growing number of new reports suggest that additional pathways are involved in the regulation of activity and levels of CUGBP1 in DM1 and DM2 cells.
Regulation (regulation) of Gene_expression (levels) of CUGBP1
1) Confidence 0.36 Published 2010 Journal Current Genomics Section Body Doc Link PMC2874224 Disease Relevance 0.06 Pain Relevance 0
Since CUGBP1 has been not found in the nuclear CUG and CCUG aggregates, nuclear CUG and CCUG foci do not appear to affect CUGBP1 levels.
Spec (appear) Regulation (affect) of Gene_expression (levels) of CUGBP1
2) Confidence 0.36 Published 2010 Journal Current Genomics Section Body Doc Link PMC2874224 Disease Relevance 0.12 Pain Relevance 0
To test if nuclear Cug-bp1 levels were altered in ?
Regulation (altered) of Gene_expression (levels) of Cug-bp1
3) Confidence 0.05 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2597774 Disease Relevance 0 Pain Relevance 0

General Comments

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