INT255180

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Context Info
Confidence 0.58
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 8
Disease Relevance 2.67
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (FABP6) cytosol (FABP6) small molecule metabolic process (FABP6)
lipid metabolic process (FABP6) cytoplasm (FABP6)
Anatomy Link Frequency
plasma 4
blood 2
ileum 1
jejunum 1
FABP6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 8 99.54 Very High Very High Very High
Inflammation 16 96.88 Very High Very High Very High
Inflammatory response 24 38.92 Quite Low
ischemia 16 5.00 Very Low Very Low Very Low
Spinal cord 8 5.00 Very Low Very Low Very Low
Analgesic 8 5.00 Very Low Very Low Very Low
Morphine 8 5.00 Very Low Very Low Very Low
Paracetamol 8 5.00 Very Low Very Low Very Low
Opioid 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 32 96.88 Very High Very High Very High
Cv General 4 Under Development 8 96.20 Very High Very High Very High
Pressure Volume 2 Under Development 200 95.68 Very High Very High Very High
Death 24 90.08 High High
Hemorrhagic Shock 16 76.88 Quite High
Diuresis 24 76.48 Quite High
Fever 8 74.80 Quite High
Urinary Tract Infection 8 73.60 Quite High
Pneumonia 8 70.96 Quite High
Wound Infection 8 69.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Plasma concentration of I-FABP, I-BABP and urinary expression of claudin-3 increased rapidly and significantly after the onset of surgery in most children.
Gene_expression (expression) of I-BABP in Plasma
1) Confidence 0.58 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2599890 Disease Relevance 0.23 Pain Relevance 0
Plasma levels of I-FABP, I-BABP were significantly negatively correlated with MAP at ½ hour before blood sampling (?
Gene_expression (levels) of I-BABP in blood
2) Confidence 0.58 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2599890 Disease Relevance 0.26 Pain Relevance 0
Interestingly, plasma levels of I-FABP, I-BABP were significantly negatively correlated with MAP at ½ hour before blood sampling (correlation: ?
Gene_expression (levels) of I-BABP in plasma
3) Confidence 0.58 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2599890 Disease Relevance 0.29 Pain Relevance 0
Next, also circulating levels of Ileal-Bile Acid Binding Protein (I-BABP), which is exclusively present in mature enterocytes of the jejunum and ileum, were assessed [23].
Gene_expression (present) of I-BABP in ileum associated with bile
4) Confidence 0.51 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2599890 Disease Relevance 0.32 Pain Relevance 0.10
To this end within-person correlations were studied between circulating levels of I-FABP, I-BABP and intraoperative MAP at ½ hour before the blood sample was collected in which FABP concentration was measured, and PrCO2, Pr-aCO2-gap at the same moment of blood sampling.
Gene_expression (levels) of I-BABP in blood
5) Confidence 0.45 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2599890 Disease Relevance 0.30 Pain Relevance 0
0.028), respectively), whereas no correlation was observed between plasma levels of I-BABP and PrCO2 or Pr-aCO2-gap.
Gene_expression (levels) of I-BABP in plasma
6) Confidence 0.45 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2599890 Disease Relevance 0.69 Pain Relevance 0
Similar to the I-FABP levels, mean I-BABP plasma concentrations also increased significantly between 2 and 8 hours after start of surgery compared to baseline values in most of the patients (Figure 1b).
Gene_expression (levels) of I-BABP in plasma
7) Confidence 0.44 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2599890 Disease Relevance 0.26 Pain Relevance 0
Next, also circulating levels of Ileal-Bile Acid Binding Protein (I-BABP), which is exclusively present in mature enterocytes of the jejunum and ileum, were assessed [23].
Gene_expression (present) of I-BABP in jejunum associated with bile
8) Confidence 0.17 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2599890 Disease Relevance 0.32 Pain Relevance 0.10

General Comments

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