INT255194

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Context Info
Confidence 0.35
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 4.26
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Fbn1) proteinaceous extracellular matrix (Fbn1)
Fbn1 (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 43 99.56 Very High Very High Very High
cytokine 3 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibrosis 45 99.56 Very High Very High Very High
Cleidocranial Dysplasia 64 96.00 Very High Very High Very High
Syndrome 96 95.76 Very High Very High Very High
Injury 18 88.80 High High
Tracheal Stenosis 2 86.80 High High
Facies 4 83.48 Quite High
Systemic Sclerosis 22 82.56 Quite High
Growth Problems 6 82.56 Quite High
Contracture 8 78.32 Quite High
Dislocations 2 76.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
has an established association with increased fibrosis and that the mutated FBN-1 binds more TGF-?
FBN-1 Binding (binds) of associated with fibrosis
1) Confidence 0.35 Published 2008 Journal Radiat Oncol Section Body Doc Link PMC2599892 Disease Relevance 1.41 Pain Relevance 0.28
ADAMTSL2 binds LTBP1 [20], whose domain structure resembles the fibrillins, although direct association between ADAMTSL2 and fibrillin-1 has not yet been reported.
fibrillin-1 Binding (association) of
2) Confidence 0.19 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2941456 Disease Relevance 2.02 Pain Relevance 0.07
binding protein, which binds fibrillin-1.
fibrillin-1 Binding (binds) of
3) Confidence 0.18 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2941456 Disease Relevance 0.83 Pain Relevance 0

General Comments

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