INT255240

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Context Info
Confidence 0.22
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.42
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Nsg1)
Nsg1 (Mus musculus)
Pain Link Frequency Relevance Heat
Catecholamine 8 98.20 Very High Very High Very High
gABA 4 80.16 Quite High
antagonist 4 77.28 Quite High
dopamine receptor 6 76.84 Quite High
Inflammation 42 75.12 Quite High
Ventral tegmentum 4 71.08 Quite High
Nucleus accumbens 10 70.12 Quite High
long-term potentiation 2 60.08 Quite High
cytokine 4 55.32 Quite High
addiction 4 40.88 Quite Low
Disease Link Frequency Relevance Heat
Cleidocranial Dysplasia 3 94.16 High High
Carcinoma 5 93.04 High High
Colitis 5 90.00 High High
INFLAMMATION 42 75.12 Quite High
Retinoblastoma 1 41.52 Quite Low
Apoptosis 10 37.52 Quite Low
Sprains And Strains 115 34.36 Quite Low
Neurodegenerative Disease 2 33.12 Quite Low
Inflammatory Bowel Disease 20 5.00 Very Low Very Low Very Low
Cancer 19 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Downstream targets of Comt participate in cytoskeletal regulation (Cmip, Etnk1, and Ptprd), intracellular signaling (Cdc42, Araf, Hipk2, Cmip, Etnk1, Ptprd, and Rasgrp1), transport (Stau1, Adam10, Dnajc10, Mcoln1, Golga3, Arl7, Spo, Pitpnb, Ddx47, Capns1, and Kif5a), receptor/channel trafficking (Palm, Akap9, Sqstm1, Cntn2, Nsg1, and Dlgap1), synaptic maintenance and plasticity (Apba1, Tle3, Slit3, Slc12a6, Elavl4, and Syt1), transcriptional regulation (Nipbl, Myt1l, Ncor1, Jundm2, and Tef), and catecholamine metabolism (Maoa).
Regulation (regulation) of Nsg1 associated with catecholamine
1) Confidence 0.22 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2923157 Disease Relevance 0 Pain Relevance 0.27
Downstream targets of Comt participate in cytoskeletal regulation (Cmip, Etnk1, and Ptprd), intracellular signaling (Cdc42, Araf, Hipk2, Cmip, Etnk1, Ptprd, and Rasgrp1), transport (Stau1, Adam10, Dnajc10, Mcoln1, Golga3, Arl7, Spo, Pitpnb, Ddx47, Capns1, and Kif5a), receptor/channel trafficking (Palm, Akap9, Sqstm1, Cntn2, Nsg1, and Dlgap1), synaptic maintenance and plasticity (Apba1, Tle3, Slit3, Slc12a6, Elavl4, and Syt1), transcriptional regulation (Nipbl, Myt1l, Ncor1, Jundm2, and Tef), and catecholamine metabolism (Maoa).
Regulation (regulation) of Nsg1 associated with catecholamine
2) Confidence 0.22 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2923157 Disease Relevance 0 Pain Relevance 0.27
Genes involved in the cell cycle process such as the protooncogene c-myc, cyclins and p21 are regulated by this mechanism.
Regulation (regulated) of p21
3) Confidence 0.05 Published 2008 Journal Biomarker Insights Section Body Doc Link PMC2600574 Disease Relevance 0.42 Pain Relevance 0.10

General Comments

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