INT255260

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Context Info
Confidence 0.20
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.42
Pain Relevance 0.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Cd47) plasma membrane (Cd47)
Anatomy Link Frequency
lung 1
thymus 1
intestine 1
Cd47 (Mus musculus)
Tsp1 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 9 98.20 Very High Very High Very High
Inflammation 126 89.84 High High
cytokine 12 7.28 Low Low
chemokine 3 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 126 89.84 High High
Apoptosis 30 81.60 Quite High
Adhesions 9 71.76 Quite High
Retinoblastoma 3 70.32 Quite High
Leukocytosis 3 47.76 Quite Low
Colitis 15 45.80 Quite Low
Carcinoma 15 44.40 Quite Low
Cleidocranial Dysplasia 9 43.80 Quite Low
Pneumonia 3 38.80 Quite Low
Hyperplasia 9 35.28 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Upon binding with CD47, TSP1 promotes the activation of thymus-derived CD4+ CD25+ T regulatory cells (Tregs).
CD47 Binding (binding) of TSP1 in thymus
1) Confidence 0.20 Published 2008 Journal Biomarker Insights Section Body Doc Link PMC2600574 Disease Relevance 0.50 Pain Relevance 0.23
By interacting with CD47, TSP1 might contribute to the quiescence state and self-tolerance in tissues such as intestine and lung.
CD47 Binding (interacting) of TSP1 in lung associated with tolerance
2) Confidence 0.20 Published 2008 Journal Biomarker Insights Section Body Doc Link PMC2600574 Disease Relevance 0.46 Pain Relevance 0.22
By interacting with CD47, TSP1 might contribute to the quiescence state and self-tolerance in tissues such as intestine and lung.
CD47 Binding (interacting) of TSP1 in intestine associated with tolerance
3) Confidence 0.07 Published 2008 Journal Biomarker Insights Section Body Doc Link PMC2600574 Disease Relevance 0.46 Pain Relevance 0.22

General Comments

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