INT255285

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Context Info
Confidence 0.07
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Snap25, Stx1a) endosome (Snap25) transport (Stx1a)
vesicle-mediated transport (Stx1a) protein binding, bridging (Stx1a) protein complex (Stx1a)
Snap25 (Mus musculus)
Stx1a (Mus musculus)
Pain Link Frequency Relevance Heat
Neurotransmitter 11 99.72 Very High Very High Very High
Calcium channel 8 99.20 Very High Very High Very High
GABAergic 45 89.28 High High
Action potential 11 73.48 Quite High
Pyramidal cell 8 5.00 Very Low Very Low Very Low
Thalamus 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 1 5.00 Very Low Very Low Very Low
Hypersensitivity 1 5.00 Very Low Very Low Very Low
Dislocations 1 5.00 Very Low Very Low Very Low
Leukemia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition to a well-documented role in membrane fusion for neuroexocytosis and neurotransmitter release, the t-SNAREs SNAP-25 and syntaxin 1 also associate with voltage-gated calcium channels (VGCCs) where they are thought to modulate steady-state inactivation of channel opening thereby regulating calcium currents in response to membrane depolarization [see ref. [6] for review].
t-SNAREs SNAP-25 Binding (associate) of syntaxin 1 associated with neurotransmitter and calcium channel
1) Confidence 0.07 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2600647 Disease Relevance 0 Pain Relevance 0.33

General Comments

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