INT255303

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Context Info
Confidence 0.27
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 0.90
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Mgst1) endoplasmic reticulum (Mgst1) nucleus (Mgst1)
Mgst1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 29 94.56 High High
Opioid 1 74.00 Quite High
Multiple sclerosis 1 55.92 Quite High
sodium channel 124 50.00 Quite Low
adenocard 30 50.00 Quite Low
Antinociceptive 22 50.00 Quite Low
Pain 4 44.76 Quite Low
Nav1.2 176 39.64 Quite Low
agonist 5 33.36 Quite Low
tolerance 1 29.56 Quite Low
Disease Link Frequency Relevance Heat
Sprains And Strains 6 96.16 Very High Very High Very High
INFLAMMATION 30 94.56 High High
Cancer 34 93.04 High High
Atherosclerosis 9 90.56 High High
Diabetes Mellitus 13 88.56 High High
Demyelinating Disease 1 55.92 Quite High
Infection 52 50.00 Quite Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 15 50.00 Quite Low
Body Weight 1 46.12 Quite Low
Pain 6 44.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The supernatant containing secreted GST-mNT5E was filtered (0.45 ?
Localization (secreted) of GST
1) Confidence 0.27 Published 2010 Journal Mol Pain Section Body Doc Link PMC2874211 Disease Relevance 0 Pain Relevance 0
For in vitro GST pull-down assay, GST by itself or a GST-Bak?
Localization (itself) of GST
2) Confidence 0.06 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2752191 Disease Relevance 0.10 Pain Relevance 0
Antioxidant action is manifested by a decrease of malondialdehyde (MDA) formation via lipid peroxidation and an increase of hepatic antioxidative enzymes and antioxidants such as glutathione peroxidase (GPX), glutathione reductase (GR), catalase (CAT), superoxide dismutase (SOD) and glutathione S transferase (GST).
Localization (transferase) of GST
3) Confidence 0.06 Published 2010 Journal Chin Med Section Body Doc Link PMC2881933 Disease Relevance 0.63 Pain Relevance 0.12
Recombinant proteins were released from GST by incubating beads with thrombin, and further purified on a Superdex 200 column equilibrated in 100 mM NaCl, 20 mM HEPES, pH 7.3 (buffer A).
Localization (released) of GST
4) Confidence 0.04 Published 2009 Journal Neuron Section Body Doc Link PMC2697323 Disease Relevance 0.06 Pain Relevance 0.03
Approximately 5–7 fmol of GST fusion proteins and GST were immobilized in flow cells via anti-GST polyclonal goat antibody covalently coupled using the amine-coupling chemistry.
Localization (immobilized) of GST
5) Confidence 0.03 Published 2008 Journal The Journal of Cell Biology Section Body Doc Link PMC2600743 Disease Relevance 0.06 Pain Relevance 0
Approximately 5–7 fmol of GST fusion proteins and GST were immobilized in flow cells via anti-GST polyclonal goat antibody covalently coupled using the amine-coupling chemistry.
Localization (immobilized) of GST
6) Confidence 0.03 Published 2008 Journal The Journal of Cell Biology Section Body Doc Link PMC2600743 Disease Relevance 0.06 Pain Relevance 0

General Comments

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