INT25539

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Context Info
Confidence 0.45
First Reported 1989
Last Reported 2008
Negated 3
Speculated 0
Reported most in Body
Documents 9
Total Number 10
Disease Relevance 2.74
Pain Relevance 0.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transport (AVP) cell-cell signaling (AVP) response to stress (AVP)
signal transducer activity (AVP) cytosol (AVP) extracellular space (AVP)
Anatomy Link Frequency
plasma 8
AVP (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 14 97.36 Very High Very High Very High
noradrenaline 26 93.88 High High
Dopamine 4 93.28 High High
cINOD 2 91.08 High High
corticosteroid 2 67.56 Quite High
Catecholamine 25 66.80 Quite High
abdominal pain 1 65.20 Quite High
headache 4 63.92 Quite High
Neuropeptide 42 57.80 Quite High
Inflammatory response 1 37.32 Quite Low
Disease Link Frequency Relevance Heat
Hyponatremia 186 99.80 Very High Very High Very High
Natriuresis 8 99.04 Very High Very High Very High
Pressure And Volume Under Development 29 97.80 Very High Very High Very High
Hypotension 17 96.16 Very High Very High Very High
INFLAMMATION 4 90.52 High High
Pressure Volume 2 Under Development 50 89.44 High High
Cv General 2 Under Development 73 86.04 High High
Myocardial Infarction 50 76.72 Quite High
Hypertension 2 74.24 Quite High
Endotoxemia 18 71.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Should the infusion rate be titrated against MAP or AVP levels?
Regulation (titrated) of Gene_expression (levels) of AVP
1) Confidence 0.45 Published 2005 Journal Crit Care Section Body Doc Link PMC1175907 Disease Relevance 0.59 Pain Relevance 0.29
The purpose was to measure the effect of ibuprofen on urinary excretion of aquaporin-2 (u-AQP2), urinary output, urinary osmolality (u-osm) and plasma concentration of vasopressin (AVP) in a dose-response study using placebo and ibuprofen 600mg and 1200mg.
Regulation (effect) of Gene_expression (excretion) of AVP in plasma
2) Confidence 0.44 Published 2001 Journal Scand. J. Clin. Lab. Invest. Section Abstract Doc Link 11768323 Disease Relevance 0.09 Pain Relevance 0.18
Effects of AVP infusion in the AVP group
Regulation (Effects) of Gene_expression (group) of AVP
3) Confidence 0.43 Published 2006 Journal Crit Care Section Body Doc Link PMC1751059 Disease Relevance 0.30 Pain Relevance 0
Effects of AVP infusion in the AVP group
Regulation (Effects) of Gene_expression (infusion) of AVP
4) Confidence 0.43 Published 2006 Journal Crit Care Section Body Doc Link PMC1751059 Disease Relevance 0.30 Pain Relevance 0
In the dysregulated state where AVP is excessively produced and released irrespective of hypoosmolality, profound water retention and hyponatremia may occur (Baylis 2003).


Regulation (dysregulated) of Gene_expression (produced) of AVP associated with hyponatremia and pressure and volume under development
5) Confidence 0.42 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2504060 Disease Relevance 0.59 Pain Relevance 0
With the exception of a slight increase in vasopressin level in the 40 mg/d treatment group, vasopressin levels in general, did not change significantly over the 12 hour study period.
Neg (not) Regulation (change) of Gene_expression (levels) of vasopressin
6) Confidence 0.42 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2504060 Disease Relevance 0.13 Pain Relevance 0
Dysregulated state: AVP excess and hyponatremia
Regulation (Dysregulated) of Gene_expression (excess) of AVP associated with hyponatremia
7) Confidence 0.36 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2504060 Disease Relevance 0.55 Pain Relevance 0
There was no significant difference in plasma AVP and OT levels between the control and the experimental ewes to i.c.v. injection (AVP: F8,1 = 0.37, OT: F8,1 = 0.23, both P > 0.05).
Neg (no) Regulation (difference) of Gene_expression (levels) of plasma AVP in plasma
8) Confidence 0.26 Published 2008 Journal BMC Dev Biol Section Body Doc Link PMC2570685 Disease Relevance 0 Pain Relevance 0.03
In the control group, i.c.v. injection of the vehicle did not change the maternal and fetal plasma AVP or OT levels.
Neg (not) Regulation (change) of Gene_expression (levels) of plasma AVP in plasma
9) Confidence 0.26 Published 2008 Journal BMC Dev Biol Section Body Doc Link PMC2570685 Disease Relevance 0 Pain Relevance 0
[Effects of surgical intervention on plasma levels of antidiuretic hormone and alpha-human atrial natriuretic polypeptide under sevoflurane anesthesia].
Regulation (Effects) of Gene_expression (levels) of antidiuretic hormone in plasma associated with natriuresis and anesthesia
10) Confidence 0.23 Published 1989 Journal Masui Section Title Doc Link 2530370 Disease Relevance 0.19 Pain Relevance 0.39

General Comments

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