INT255691

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (VEGFA, Flt1) cell differentiation (Flt1) endosome (Flt1)
Golgi apparatus (Flt1) extracellular space (VEGFA) extracellular region (VEGFA)
VEGFA (Homo sapiens)
Flt1 (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 6 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Thoracotomy 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coronary Heart Disease 14 50.00 Quite Low
Hypoxia 116 39.12 Quite Low
Hypertrophy 50 5.00 Very Low Very Low Very Low
Cyanosis 16 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 6 5.00 Very Low Very Low Very Low
Reperfusion Injury 6 5.00 Very Low Very Low Very Low
Body Weight 4 5.00 Very Low Very Low Very Low
Ischemic Heart Disease 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Based on this information, excessive expression of VEGFR-1 could result in increased binding to VEGF ligand, resulting in competitive suppression of VEFGR-2 activation and the angiogenic response.
Positive_regulation (result) of VEGF Binding (binding) of VEGFR-1
1) Confidence 0.02 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2603310 Disease Relevance 0 Pain Relevance 0
Based on this information, excessive expression of VEGFR-1 could result in increased binding to VEGF ligand, resulting in competitive suppression of VEFGR-2 activation and the angiogenic response.
Positive_regulation (increased) of VEGF Binding (binding) of VEGFR-1
2) Confidence 0.02 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2603310 Disease Relevance 0 Pain Relevance 0

General Comments

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