INT255705

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.69
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 0.75
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (C12orf39) nucleolus (C12orf39) nucleus (C12orf39)
Anatomy Link Frequency
reticular formation 1
pancreas 1
brain 1
serotonergic neurons 1
C12orf39 (Homo sapiens)
Pain Link Frequency Relevance Heat
Central grey 35 99.82 Very High Very High Very High
Locus ceruleus 5 89.76 High High
Neuropeptide 155 23.16 Low Low
substance P 5 15.60 Low Low
Enkephalin 10 5.36 Low Low
Neurotransmitter 15 5.00 Very Low Very Low Very Low
opiate 10 5.00 Very Low Very Low Very Low
orphanin 10 5.00 Very Low Very Low Very Low
alcohol 5 5.00 Very Low Very Low Very Low
Dynorphin 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 35 99.82 Very High Very High Very High
Lung Cancer 5 84.60 Quite High
Hypersensitivity 35 44.36 Quite Low
Stress 20 5.00 Very Low Very Low Very Low
Decapitation 5 5.00 Very Low Very Low Very Low
Anxiety Disorder 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Northern analysis using a human tissue blot (Clontech) showed the presence of preproNPQ mRNA in brain and pancreas, but most prominently in the kidney (Figure 6).
Transcription (presence) of NPQ in pancreas
1) Confidence 0.69 Published 2009 Journal PLoS Computational Biology Section Body Doc Link PMC2603333 Disease Relevance 0.08 Pain Relevance 0
At the level of the caudal periaqueductal gray (PAG), preproNPQ mRNA expression is restricted to the ventrolateral quadrant of this structure (Figure 8) with some scattered signal in the underlying reticular formation.
Transcription (expression) of NPQ in reticular formation associated with central grey
2) Confidence 0.69 Published 2009 Journal PLoS Computational Biology Section Body Doc Link PMC2603333 Disease Relevance 0.35 Pain Relevance 0.21
At this level of the neuraxis preproNPQ mRNA is located quite a bit lateral to the majority of the midline serotonergic neurons, as determined by examination of mRNA distribution of the synthetic enzyme tryptophan hydroxylase 2 (TPH2) (Figure 7J–L), though there is some overlap with the laterally displaced TPH2-positive neurons (Figure 7L).
Transcription (distribution) of NPQ in serotonergic neurons
3) Confidence 0.67 Published 2009 Journal PLoS Computational Biology Section Body Doc Link PMC2603333 Disease Relevance 0.24 Pain Relevance 0.16
In order to determine if the preproNPQ transcript could be detected in various human tissues, we used Ambion's First Choice Human Blot (a nylon membrane bound with 3 mg RNA from various human tissues, Ambion Inc, TX).
Transcription (detected) of NPQ
4) Confidence 0.52 Published 2009 Journal PLoS Computational Biology Section Body Doc Link PMC2603333 Disease Relevance 0 Pain Relevance 0
Northern analysis using a human tissue blot (Clontech) showed the presence of preproNPQ mRNA in brain and pancreas, but most prominently in the kidney (Figure 6).
Transcription (presence) of NPQ in brain
5) Confidence 0.24 Published 2009 Journal PLoS Computational Biology Section Body Doc Link PMC2603333 Disease Relevance 0.08 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox