INT255708

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Context Info
Confidence 0.53
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.84
Pain Relevance 2.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (PAG1) plasma membrane (PAG1) intracellular (PAG1)
Anatomy Link Frequency
reticular formation 1
PAG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Central grey 100 100.00 Very High Very High Very High
Morphine 79 98.32 Very High Very High Very High
antinociception 9 97.20 Very High Very High Very High
tolerance 13 93.72 High High
Rostral ventromedial medulla 51 81.64 Quite High
projection neuron 2 77.80 Quite High
analgesia 23 77.52 Quite High
Locus ceruleus 2 75.56 Quite High
Antinociceptive 5 57.80 Quite High
Potency 7 56.72 Quite High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 102 100.00 Very High Very High Very High
Pain 30 50.00 Quite Low
Lung Cancer 1 22.56 Low Low
Hypersensitivity 7 5.00 Very Low Very Low Very Low
Inflammatory Pain 5 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Hyperalgesia 3 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
the PAG in males and females, it was suboptimal in producing behaviorally defined
Transcription (suboptimal) of PAG associated with central grey
1) Confidence 0.53 Published 2009 Journal Neural Plasticity Section Body Doc Link PMC2633449 Disease Relevance 0.49 Pain Relevance 1.86
At the level of the caudal periaqueductal gray (PAG), preproNPQ mRNA expression is restricted to the ventrolateral quadrant of this structure (Figure 8) with some scattered signal in the underlying reticular formation.
Transcription (expression) of PAG in reticular formation associated with central grey
2) Confidence 0.08 Published 2009 Journal PLoS Computational Biology Section Body Doc Link PMC2603333 Disease Relevance 0.35 Pain Relevance 0.21

General Comments

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