INT255723

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Context Info
Confidence 0.39
First Reported 2008
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.30
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ptch1) extracellular region (Ptch1) plasma membrane (Ptch1)
Ptch1 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 6 18.84 Low Low
Inflammation 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
member 8 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Neuronal excitability 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Calcium channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 92 99.98 Very High Very High Very High
Skin Cancer 1 99.12 Very High Very High Very High
Cancer 3 91.04 High High
Necrosis 1 63.44 Quite High
Hyperglycemia 7 50.84 Quite High
Insulin Resistance 25 50.00 Quite Low
Obesity 10 47.92 Quite Low
Body Weight 5 36.04 Quite Low
Impaired Glucose Tolerance 3 18.84 Low Low
Diabetes Mellitus 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hence overexpression of PTCH1 by AICD could be a protective measure of cells against tumorigenesis.
Positive_regulation (overexpression) of Gene_expression (overexpression) of PTCH1
1) Confidence 0.39 Published 2011 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2935165 Disease Relevance 0.19 Pain Relevance 0
Interestingly, HS+MES treatment enhanced the insulin-stimulated IR?
Positive_regulation (enhanced) of Gene_expression (treatment) of MES associated with shock
2) Confidence 0.22 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2603588 Disease Relevance 1.11 Pain Relevance 0

General Comments

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