INT255734

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Context Info
Confidence 0.09
First Reported 2008
Last Reported 2008
Negated 0
Speculated 2
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.46
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Ptch1, Ins1) extracellular space (Ins1) signal transduction (Ptch1)
plasma membrane (Ptch1) carbohydrate metabolic process (Ins1) cytoplasm (Ins1)
Ptch1 (Mus musculus)
Ins1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 2 29.20 Quite Low
Inflammation 6 28.80 Quite Low
tolerance 12 21.16 Low Low
Pain 4 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 184 99.98 Very High Very High Very High
Diabetes Mellitus 22 98.52 Very High Very High Very High
Toxicity 2 85.40 High High
Disease 2 80.80 Quite High
Hyperinsulinism 2 80.12 Quite High
Insulin Resistance 50 75.04 Quite High
Hypertrophy 2 68.24 Quite High
Heat Stress Disorders 2 65.20 Quite High
Body Weight 10 50.32 Quite High
Obesity 20 32.56 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We also examined the effect of MES on downstream molecules of insulin signaling.
MES Spec (examined) Regulation (effect) of insulin
1) Confidence 0.09 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2603588 Disease Relevance 0.22 Pain Relevance 0
These data suggest that HS+MES may directly affect major insulin target tissues or may exert an anti-diabetic effect in one tissue, leading to secondary effects in the other tissues.
MES Spec (may) Regulation (affect) of insulin associated with diabetes mellitus and shock
2) Confidence 0.09 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2603588 Disease Relevance 1.24 Pain Relevance 0

General Comments

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