INT255741

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Context Info
Confidence 0.09
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 2.21
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Ptch1, Ins1) extracellular space (Ins1) signal transduction (Ptch1)
plasma membrane (Ptch1) carbohydrate metabolic process (Ins1) cytoplasm (Ins1)
Anatomy Link Frequency
fat 2
Ptch1 (Mus musculus)
Ins1 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 12 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 184 100.00 Very High Very High Very High
Insulin Resistance 50 100.00 Very High Very High Very High
Hyperglycemia 14 91.68 High High
Fatty Liver 2 71.60 Quite High
Obesity 20 68.88 Quite High
Diabetes Mellitus 22 5.00 Very Low Very Low Very Low
Body Weight 10 5.00 Very Low Very Low Very Low
Impaired Glucose Tolerance 6 5.00 Very Low Very Low Very Low
INFLAMMATION 6 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because insulin resistance is characterized by a marked reduction in insulin-stimulated PI3K-mediated activation of Akt, we asked whether MES could increase Akt phosphorylation and ameliorate insulin resistance.
MES Positive_regulation (increase) of Phosphorylation (phosphorylation) of insulin associated with insulin resistance
1) Confidence 0.09 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2603588 Disease Relevance 0.92 Pain Relevance 0
MES (12 V)+mild HS treatment of high fat-fed mice also increased the phosphorylation of insulin receptor ?
MES Positive_regulation (increased) of Phosphorylation (phosphorylation) of insulin in fat associated with shock
2) Confidence 0.09 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2603588 Disease Relevance 1.29 Pain Relevance 0

General Comments

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