INT255754

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.14
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.73
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

carbohydrate metabolic process (Ins1, Akt1) cytoplasm (Ins1, Akt1) transport (Akt1)
aging (Akt1) enzyme binding (Akt1) cytosol (Akt1)
Ins1 (Mus musculus)
Akt1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 4 65.36 Quite High
Inflammation 6 63.48 Quite High
tolerance 12 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Insulin Resistance 50 99.40 Very High Very High Very High
Shock 184 88.16 High High
Diabetes Mellitus 22 87.48 High High
Hyperglycemia 14 85.28 High High
Wound Healing 2 81.84 Quite High
Cancer 4 69.44 Quite High
Pain 4 65.36 Quite High
Fracture Healing 2 64.40 Quite High
INFLAMMATION 6 63.48 Quite High
Obesity 20 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There is consensus that a marked reduction in insulin-stimulated PI3K-mediated activation of Akt results in decreased insulin sensitivity in vivo [14], [15], [16], [17].
Negative_regulation (reduction) of insulin Positive_regulation (activation) of Akt
1) Confidence 0.14 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2603588 Disease Relevance 0.86 Pain Relevance 0.10
Because insulin resistance is characterized by a marked reduction in insulin-stimulated PI3K-mediated activation of Akt, we asked whether MES could increase Akt phosphorylation and ameliorate insulin resistance.
Negative_regulation (reduction) of insulin Positive_regulation (activation) of Akt associated with insulin resistance
2) Confidence 0.14 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2603588 Disease Relevance 0.88 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox