INT255804

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.36
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6) mitochondrion (DSP) extracellular region (Il6)
structural molecule activity (DSP) plasma membrane (DSP) protein binding, bridging (DSP)
DSP (Homo sapiens)
Il6 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 8 100.00 Very High Very High Very High
Inflammation 18 88.88 High High
Kinase C 1 73.80 Quite High
substance P 2 65.56 Quite High
Inflammatory response 5 42.16 Quite Low
cINOD 11 5.00 Very Low Very Low Very Low
Dextromethorphan 10 5.00 Very Low Very Low Very Low
Enkephalin 2 5.00 Very Low Very Low Very Low
nMDA receptor 2 5.00 Very Low Very Low Very Low
narcan 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 26 88.88 High High
Death 2 61.44 Quite High
Drug Induced Neurotoxicity 7 51.92 Quite High
Disease 50 10.40 Low Low
Stress 8 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 5 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 5 5.00 Very Low Very Low Very Low
Toxicity 4 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, both DPI and catalase (an enzyme that catalyzes the decomposition of H2O2 to water and oxygen) were shown to suppress LPS-induced expression of cytokines (IL-1, IL-6, and TNF?)
DPI Negative_regulation (suppress) of Gene_expression (expression) of IL-6 associated with cytokine
1) Confidence 0.01 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2604892 Disease Relevance 0.36 Pain Relevance 0.36

General Comments

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