INT255811

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.67
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (GNAS, MAPT) plasma membrane (GNAS, MAPT) small molecule metabolic process (GNAS)
intracellular (GNAS) enzyme binding (MAPT) GTPase activity (GNAS)
Anatomy Link Frequency
PSP 1
GNAS (Homo sapiens)
MAPT (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 1 76.44 Quite High
Inflammation 1 75.96 Quite High
Central nervous system 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Tauopathy 18 100.00 Very High Very High Very High
Supranuclear Palsy 15 99.92 Very High Very High Very High
Disease 20 99.36 Very High Very High Very High
Spinal Muscular Atrophy 8 84.08 Quite High
INFLAMMATION 1 75.96 Quite High
Neurodegenerative Disease 5 44.88 Quite Low
Motor Neuron Diseases 4 17.76 Low Low
Frontotemporal Dementia 3 14.16 Low Low
Parkinson's Disease 3 11.84 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Aberrant inclusion of exon 10 into tau mRNA promotes the increased production of 4R-tau and has been increasingly recognized as one of the causes of tauopathies in FTDP-17, PSP, and many AD patients [51,64-66,76].
exon Binding (recognized) of FTDP-17 in PSP associated with tauopathy, supranuclear palsy and disease
1) Confidence 0.00 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2604894 Disease Relevance 0.67 Pain Relevance 0.11

General Comments

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