INT255902

Context Info Confidence 0.17 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.93 Pain Relevance 0.42

cytosol (MAPK14) nucleoplasm (MAPK14) signal transduction (MAPK14) nucleus (MAPK14) response to stress (MAPK14) cytoplasm (MAPK14)

MAPK14 (Homo sapiens)

Pain Link Frequency Relevance Heat Central nervous system 42 99.54 cytokine 68 97.28 Eae 2 50.92 Bioavailability 2 36.96 Inflammation 16 16.32 Inflammatory response 4 5.00 rheumatoid arthritis 4 5.00 Pain 2 5.00 Crohn's disease 2 5.00 Hippocampus 2 5.00

Disease Link Frequency Relevance Heat Disease 18 99.12 Brain Injury 2 89.20 Injury 4 88.40 Alzheimer's Dementia 4 87.40 Brain Hemorrhage 2 77.56 Amyloid Plaque 2 64.28 Neurodegenerative Disease 8 56.16 Targeted Disruption 4 54.28 Dementia 2 41.68 INFLAMMATION 20 16.32

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

MAPK as a therapeutic approach in some CNS disorders and provide causative links between p38?

Positive_regulation (causative) of p38 Binding (links) of associated with central nervous system

1) Confidence 0.17 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2604896 Disease Relevance 0.44 Pain Relevance 0.28

An in vivo causative link between p38?

Positive_regulation (causative) of p38 Binding (link) of

2) Confidence 0.17 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2604896 Disease Relevance 0.49 Pain Relevance 0.14

General Comments

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