INT255985

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Context Info
Confidence 0.52
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.37
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il1rn) extracellular region (Il1rn) nucleus (Il1rn)
lipid metabolic process (Il1rn) cytoplasm (Il1rn)
Il1rn (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate 2 71.28 Quite High
Somatostatin 2 64.56 Quite High
bradykinin 2 63.12 Quite High
Enkephalin 2 61.84 Quite High
Dynorphin 2 60.88 Quite High
Cholecystokinin 2 57.28 Quite High
Bioavailability 2 7.92 Low Low
Potency 6 5.00 Very Low Very Low Very Low
long-term potentiation 4 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pre-term Labor 2 99.12 Very High Very High Very High
Targeted Disruption 10 78.72 Quite High
Cognitive Disorder 18 51.68 Quite High
Obesity 2 14.16 Low Low
Disease 30 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 6 5.00 Very Low Very Low Very Low
Neurological Disease 4 5.00 Very Low Very Low Very Low
Amnesia 4 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, IRAP cleaves the first three residues from the amino terminus of a structurally related peptide hormone, arginine-vasopressin, more efficiently than oxytocin.
Protein_catabolism (cleaves) of IRAP
1) Confidence 0.52 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2604898 Disease Relevance 0.23 Pain Relevance 0.21
IRAP had also been cloned from a human placental cDNA library (as oxytocinase), based on the capacity of IRAP to readily cleave oxytocin in vitro [42].
Protein_catabolism (cleave) of IRAP
2) Confidence 0.52 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2604898 Disease Relevance 0.14 Pain Relevance 0.04

General Comments

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