INT256011

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Context Info
Confidence 0.64
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.05
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Lnpep) plasma membrane (Lnpep) intracellular (Lnpep)
cytoplasm (Lnpep)
Lnpep (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 6 56.16 Quite High
Thalamus 4 50.32 Quite High
Locus ceruleus 2 39.44 Quite Low
antagonist 12 5.00 Very Low Very Low Very Low
Dopamine 4 5.00 Very Low Very Low Very Low
Eae 4 5.00 Very Low Very Low Very Low
long-term potentiation 2 5.00 Very Low Very Low Very Low
Enkephalin 2 5.00 Very Low Very Low Very Low
beta blocker 2 5.00 Very Low Very Low Very Low
Onset of action 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 2 54.00 Quite High
Cognitive Disorder 62 50.00 Quite Low
Sprains And Strains 16 5.00 Very Low Very Low Very Low
Hypertension 8 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Anxiety Disorder 4 5.00 Very Low Very Low Very Low
Aging 2 5.00 Very Low Very Low Very Low
Myocardial Infarction 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To summarise the argument: the AT4 receptor and IRAP have identical binding properties for angiotensin IV, and expression of the cDNA for IRAP gives rise to a protein with the binding characteristics of the AT4 receptor.
Gene_expression (expression) of IRAP
1) Confidence 0.64 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2604899 Disease Relevance 0.05 Pain Relevance 0
Expression of cloned IRAP in cultured cells yielded a receptor with binding characteristics almost identical to those of the native AT4 receptor.
Gene_expression (Expression) of IRAP
2) Confidence 0.56 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2604899 Disease Relevance 0 Pain Relevance 0.08

General Comments

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