INT256032

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Context Info
Confidence 0.39
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.61
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ntrk3) plasma membrane (Ntrk3) kinase activity (Ntrk3)
cytoplasm (Ntrk3)
Ntrk3 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 23 94.04 High High
Nerve growth factor 59 77.12 Quite High
adenocard 1 65.68 Quite High
tricyclic antidepressant 2 33.04 Quite Low
Central nervous system 1 30.96 Quite Low
Endep 2 30.56 Quite Low
Serotonin 2 29.68 Quite Low
antidepressant 11 23.36 Low Low
Glutamate 6 22.96 Low Low
sSRI 1 20.36 Low Low
Disease Link Frequency Relevance Heat
Death 12 93.36 High High
Convulsion 4 91.20 High High
Apoptosis 20 91.00 High High
Neuroblastoma 3 90.04 High High
Middle Cerebral Artery Infarction 1 87.44 High High
Stroke 5 84.24 Quite High
Disease 23 35.64 Quite Low
Cognitive Disorder 3 35.40 Quite Low
Neuropathic Pain 1 33.40 Quite Low
Peripheral Neuropathy 2 14.52 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Deoxygedunin also elicited tyrosine phosphorylation in TrkB but not in TrkA or TrkC receptor in transfected HEK293 cells.
Phosphorylation (phosphorylation) of TrkC receptor
1) Confidence 0.39 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2903477 Disease Relevance 0.07 Pain Relevance 0
This compound binds TrkA, but not TrkB or TrkC, and causes receptor dimerization and phosphorylation.
Phosphorylation (phosphorylation) of TrkC
2) Confidence 0.23 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2604901 Disease Relevance 0.54 Pain Relevance 0.12

General Comments

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