INT256072

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.49
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ros1) cell proliferation (Ros1) extracellular region (Serpina3k)
plasma membrane (Ros1)
Serpina3k (Rattus norvegicus)
Ros1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcium channel 1 37.36 Quite Low
Inflammation 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 24 97.48 Very High Very High Very High
Apoptosis 13 75.96 Quite High
Stress 26 67.12 Quite High
Necrosis 15 57.64 Quite High
Ocular Toxicity (including Many Sub-types) 3 33.28 Quite Low
Age-related Macular Degeneration 1 30.68 Quite Low
Diabetic Retinopathy 10 30.36 Quite Low
Retina Disease 3 29.04 Quite Low
Retinal Neovascularization 1 24.64 Low Low
Nerve Degeneration 4 21.84 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using the CM-H2DCFDA probe, we showed that SERPINA3K did not block the increase of intracellular ROS levels in the cells exposed to H2O2, although it reduced cell death.
SERPINA3K Negative_regulation (block) of Positive_regulation (increase) of ROS associated with death
1) Confidence 0.04 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2605247 Disease Relevance 0.49 Pain Relevance 0

General Comments

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