INT256074

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.64
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ros1) cell proliferation (Ros1) extracellular region (Serpina3k)
plasma membrane (Ros1)
Serpina3k (Rattus norvegicus)
Ros1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Calcium channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 24 96.20 Very High Very High Very High
Necrosis 15 73.32 Quite High
Apoptosis 13 69.88 Quite High
Stress 26 66.44 Quite High
Injury 1 43.12 Quite Low
Diabetic Retinopathy 10 5.00 Very Low Very Low Very Low
Diabetes Mellitus 7 5.00 Very Low Very Low Very Low
Nerve Degeneration 4 5.00 Very Low Very Low Very Low
Ocular Toxicity (including Many Sub-types) 3 5.00 Very Low Very Low Very Low
Retina Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SERPINA3K reduced the TBHP-induced intracellular ROS generation in a dose-dependent manner (Fig. 3E), but it did not protect the cells from TBHP-induced cell death (Fig. 3B).
SERPINA3K Negative_regulation (reduced) of Gene_expression (generation) of ROS associated with death
1) Confidence 0.04 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2605247 Disease Relevance 0.64 Pain Relevance 0

General Comments

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