INT256111

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Context Info
Confidence 0.32
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.73
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Sirt1) nucleoplasm (Sirt1) nuclear envelope (Sirt1)
histone binding (Sirt1) enzyme binding (Sirt1) cytoplasm (Sirt1)
Sirt1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 2 95.16 Very High Very High Very High
Potency 1 79.12 Quite High
agonist 3 58.56 Quite High
withdrawal 1 51.44 Quite High
Hippocampus 1 36.96 Quite Low
Neuritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cardiovascular Disease 1 96.24 Very High Very High Very High
INFLAMMATION 2 95.16 Very High Very High Very High
Cancer 3 94.60 High High
Diabetes Mellitus 1 94.28 High High
Neurodegenerative Disease 6 91.76 High High
Apoptosis 32 81.40 Quite High
Neuroblastoma 10 59.44 Quite High
Death 22 50.80 Quite High
Stress 7 5.00 Very Low Very Low Very Low
Toxicity 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
An interesting and novel finding of our study is that the neuroprotection by SIRT1 is not affected by nicotinamide, a potent and noncompetitive inhibitor of the sirtuins.
Neg (not) Regulation (affected) of Gene_expression (neuroprotection) of SIRT1
1) Confidence 0.32 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2605257 Disease Relevance 0.73 Pain Relevance 0.14

General Comments

This test has worked.

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