INT256114

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Context Info
Confidence 0.19
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.70
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitosis (Sirt2) cytoskeleton (Sirt2) cell cycle (Sirt2)
cell division (Sirt2) transcription factor binding (Sirt2) cytoplasm (Sirt2)
Sirt2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 4 50.52 Quite High
agonist 6 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Neuritis 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 64 99.68 Very High Very High Very High
Stress 14 98.68 Very High Very High Very High
Neuroblastoma 20 98.48 Very High Very High Very High
Death 44 89.76 High High
INFLAMMATION 4 50.52 Quite High
Chromosomal Instability 2 46.84 Quite Low
Lifespan 2 38.28 Quite Low
Disease 6 21.76 Low Low
Motor Neuron Diseases 2 20.16 Low Low
Toxicity 10 17.20 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As observed in CGNs, SIRT2 overexpression had an apoptotic effect on untreated neuroblastoma cells.
Gene_expression (overexpression) of SIRT2 associated with neuroblastoma and apoptosis
1) Confidence 0.19 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2605257 Disease Relevance 1.43 Pain Relevance 0
SIRT2 resides mostly in the cytoplasm where it associates with microtubules and deacetylates ?
Gene_expression (resides) of SIRT2
2) Confidence 0.19 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2605257 Disease Relevance 0.27 Pain Relevance 0.03

General Comments

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