INT256136

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Context Info
Confidence 0.30
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.50
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Sirt1) nucleoplasm (Sirt1) nuclear envelope (Sirt1)
histone binding (Sirt1) enzyme binding (Sirt1) cytoplasm (Sirt1)
Sirt1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 6 72.76 Quite High
Inflammation 4 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Neuritis 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 44 92.60 High High
Cancer 6 79.72 Quite High
Apoptosis 64 79.12 Quite High
Neuroblastoma 20 39.92 Quite Low
Stress 14 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 12 5.00 Very Low Very Low Very Low
Toxicity 10 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Optic Neuritis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mutant forms of SIRT1 lacking deacetylase activity are completely neuroprotective
Negative_regulation (forms) of SIRT1 Binding (activity) of
1) Confidence 0.30 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2605257 Disease Relevance 0.25 Pain Relevance 0.04
Mutant forms of SIRT1 lacking deacetylase activity are completely neuroprotective
Negative_regulation (lacking) of SIRT1 Binding (activity) of
2) Confidence 0.30 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2605257 Disease Relevance 0.25 Pain Relevance 0.04

General Comments

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