INT25616

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Context Info
Confidence 0.60
First Reported 1989
Last Reported 1989
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Pomc) generation of precursor metabolites and energy (Pomc) extracellular space (Pomc)
extracellular region (Pomc) cell-cell signaling (Pomc) cytoplasm (Pomc)
Anatomy Link Frequency
macrophages 2
Pomc (Mus musculus)
Il1 (Mus musculus)
Pain Link Frequency Relevance Heat
Neuropeptide 2 100.00 Very High Very High Very High
opioid receptor 4 99.22 Very High Very High Very High
narcan 6 98.04 Very High Very High Very High
Opioid 2 85.68 High High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Naloxone, a competitive inhibitor of beta-endorphin opioid receptor interactions, abrogated the enhancing effects of beta-endorphin on LPS-induced IL-1 production.
beta-endorphin Regulation (effects) of Gene_expression (production) of IL-1 associated with narcan and opioid receptor
1) Confidence 0.60 Published 1989 Journal Int. Immunol. Section Abstract Doc Link 2535139 Disease Relevance 0 Pain Relevance 0.31
The role of the neuropeptide beta-endorphin on interleukin 1 (IL-1) production by murine bone marrow-derived macrophages was assessed.
beta-endorphin Regulation (role) of Gene_expression (production) of IL-1 in macrophages associated with neuropeptide
2) Confidence 0.44 Published 1989 Journal Int. Immunol. Section Abstract Doc Link 2535139 Disease Relevance 0 Pain Relevance 0.12

General Comments

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