INT256228

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Context Info
Confidence 0.26
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.62
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (EDN1) extracellular region (EDN1) plasma membrane (EDNRB)
cell-cell signaling (EDN1) cytoplasm (EDN1) signal transducer activity (EDNRB)
Anatomy Link Frequency
internal 1
EDNRB (Homo sapiens)
EDN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 57.68 Quite High
tolerance 3 34.72 Quite Low
diabetic neuropathy 4 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
peripheral neuropathy 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Brush evoked pain 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 17 99.96 Very High Very High Very High
Cardiovascular Disease 4 61.04 Quite High
INFLAMMATION 2 57.68 Quite High
Pressure And Volume Under Development 4 40.08 Quite Low
Myocardial Infarction 2 36.64 Quite Low
Impaired Glucose Tolerance 3 34.72 Quite Low
Diabetes Mellitus 53 29.52 Quite Low
Diabetic Angiopathy 13 26.40 Quite Low
Renal Disease 2 10.16 Low Low
Ocular Toxicity (including Many Sub-types) 2 9.12 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In isolated human internal mammary and porcine coronary arteries, ETB receptor mediates ET-1-induced vasoconstriction (Seo et al 1994).
ETB receptor Positive_regulation (mediates) of ET-1-induced in internal associated with increased venous pressure under development
1) Confidence 0.26 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2605330 Disease Relevance 0.62 Pain Relevance 0.03

General Comments

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