INT256248

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Context Info
Confidence 0.35
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.25
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

enzyme binding (Esr1) DNA binding (Esr1) protein complex (Esr1)
cytoplasm (Esr1) lipid binding (Esr1) nucleus (Esr1)
Esr1 (Mus musculus)
Pain Term Frequency Confidence Heat
antagonist 2 89.24 High High
ischemia 1 74.76 Quite High
aspirin 3 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
backache 1 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Term Frequency Confidence Heat
Coronary Heart Disease 6 95.84 Very High Very High Very High
Increased Venous Pressure Under Development 22 91.76 High High
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14 84.48 Quite High
Disorder Of Lipid Metabolism 33 82.48 Quite High
Hypertriglyceridemia 12 80.00 Quite High
Hyperlipidemia 4 79.08 Quite High
Cv Unclassified Under Development 1 74.76 Quite High
Acute Coronary Syndrome 1 73.32 Quite High
Stroke 1 71.40 Quite High
Myocardial Infarction 2 70.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In our opinion, the AIM HIGH and HPS2-THRIVE studies will give us answers to the question whether the combination of simvastatin with niacin ER will reduce residual cardiovascular risk in comparison to statin therapy alone.
Spec (whether) Negative_regulation (reduce) of simvastatin Spec (whether) Binding (combination) of ER
1) Confidence 0.35 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2605342 Disease Relevance 1.11 Pain Relevance 0.08

General Comments

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