INT256296

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.66
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Efnb1, Ephb1) endosome (Ephb1) cell differentiation (Efnb1)
signal transduction (Ephb1) cell adhesion (Ephb1) plasma membrane (Ephb1)
Efnb1 (Mus musculus)
Ephb1 (Mus musculus)
Pain Link Frequency Relevance Heat
Thermal hyperalgesia 20 99.16 Very High Very High Very High
nMDA receptor 10 97.32 Very High Very High Very High
Hyperalgesia 22 86.04 High High
withdrawal 21 79.80 Quite High
nMDA receptor antagonist 1 71.36 Quite High
Morphine 41 50.00 Quite Low
Physical dependence 4 50.00 Quite Low
Neuropathic pain 29 35.12 Quite Low
addiction 38 5.00 Very Low Very Low Very Low
opiate 15 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperalgesia 42 99.16 Very High Very High Very High
Hypersensitivity 4 80.32 Quite High
Nervous System Injury 26 73.80 Quite High
Neuropathic Pain 42 50.00 Quite Low
Drug Dependence 4 50.00 Quite Low
Morphine Dependence 27 5.00 Very Low Very Low Very Low
Opiate Addiction 11 5.00 Very Low Very Low Very Low
Pain 10 5.00 Very Low Very Low Very Low
Targeted Disruption 10 5.00 Very Low Very Low Very Low
Ganglion Cysts 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
EphrinB1-Fc can activate EphB receptors and evoke thermal hyperalgesia via interaction with the NMDA receptor in rats [29,51].
EphrinB1 Positive_regulation (activate) of EphB associated with nmda receptor and thermal hyperalgesia
1) Confidence 0.03 Published 2008 Journal Mol Pain Section Body Doc Link PMC2605438 Disease Relevance 0.66 Pain Relevance 0.54

General Comments

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