INT256692

Context Info Confidence 0.41 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

endoplasmic reticulum (Wfs1) neurological system process (Wfs1)

Wfs1 (Mus musculus)

Pain Link Frequency Relevance Heat gABA 4 5.00 depression 3 5.00 Migraine 1 5.00 anticonvulsant 1 5.00 Neurotransmitter 1 5.00 GABAergic 1 5.00

Disease Link Frequency Relevance Heat Stress 21 50.00 Manic Depressive Disorder 19 28.56 Oxidative Phosphorylation Disease 3 5.00 Depression 3 5.00 Convulsion 2 5.00 Optic Atrophy 1 5.00 Diabetes Mellitus 1 5.00 Epilepsy 1 5.00 Diabetes Insipidus 1 5.00 Headache 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The amount of WFS1 immnoprecipitated with anti-WFS1 antibody was also decreased with lithium (Figure 3A, lanes 3 and 4, lower panels, IP).

Negative_regulation (decreased) of WFS1

1) Confidence 0.41 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2607540 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.