INT256703

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Context Info
Confidence 0.42
First Reported 2009
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.24
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Hsp90b1, Wfs1) unfolded protein binding (Hsp90b1) protein folding (Hsp90b1)
cytosol (Hsp90b1) RNA binding (Hsp90b1) neurological system process (Wfs1)
Hsp90b1 (Mus musculus)
Wfs1 (Mus musculus)
Pain Link Frequency Relevance Heat
gABA 4 5.00 Very Low Very Low Very Low
depression 3 5.00 Very Low Very Low Very Low
Migraine 1 5.00 Very Low Very Low Very Low
anticonvulsant 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
GABAergic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Manic Depressive Disorder 19 97.96 Very High Very High Very High
Stress 21 50.36 Quite High
Oxidative Phosphorylation Disease 3 5.00 Very Low Very Low Very Low
Depression 3 5.00 Very Low Very Low Very Low
Convulsion 2 5.00 Very Low Very Low Very Low
Optic Atrophy 1 5.00 Very Low Very Low Very Low
Diabetes Mellitus 1 5.00 Very Low Very Low Very Low
Epilepsy 1 5.00 Very Low Very Low Very Low
Diabetes Insipidus 1 5.00 Very Low Very Low Very Low
Headache 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Downregulation of GRP94 may increase the amount of GRP94-free WFS1, leading to the enhancement of WFS1 function.
Negative_regulation (Downregulation) of GRP94 Spec (may) Positive_regulation (increase) of WFS1
1) Confidence 0.42 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2607540 Disease Relevance 0.24 Pain Relevance 0

General Comments

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