INT256917

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Context Info
Confidence 0.60
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.99
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Ifnar2) extracellular space (Ifnar2) extracellular region (Ifnar2)
Anatomy Link Frequency
skin 1
Ifnar2 (Mus musculus)
Pain Link Frequency Relevance Heat
IPN 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 36 98.76 Very High Very High Very High
Viral Infection 1 97.90 Very High Very High Very High
Cancer 27 95.92 Very High Very High Very High
Skin Cancer 5 74.80 Quite High
Influenza Virus Infection 2 73.44 Quite High
Cervical Cancer 9 69.28 Quite High
Apoptosis 16 66.88 Quite High
Papillomavirus Infection 14 50.00 Quite Low
Hyperplasia 5 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-JAK/Stat signaling pathway is critical for host defense against viral infection by stimulating transcription of antiviral, antiproliferative, and antitumor genes, suggesting that down-regulation of IFNAR2 and Stat-1 in skin from K14E6 transgenic mice might be critical for immune evasion and therefore for cancer development.
Localization (regulation) of IFNAR2 in skin associated with targeted disruption, cancer and viral infection
1) Confidence 0.60 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2610035 Disease Relevance 0.99 Pain Relevance 0

General Comments

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