INT256918

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Context Info
Confidence 0.24
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.71
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Irf1) DNA binding (Irf1)
Anatomy Link Frequency
skin 2
Irf1 (Mus musculus)
Pain Link Frequency Relevance Heat
IPN 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 72 99.22 Very High Very High Very High
Apoptosis 32 94.20 High High
Papillomavirus Infection 28 50.00 Quite Low
Hyperplasia 10 48.72 Quite Low
Skin Cancer 10 32.56 Quite Low
Cancer 54 24.48 Low Low
Malignant Neoplastic Disease 10 22.96 Low Low
Cervical Cancer 18 21.60 Low Low
Benign Tumor 4 17.44 Low Low
Cervical Intraepithelial Neoplasia 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Another pathway that was severely affected in skin of K14E6 transgenic mice was the immune response, showing down-regulation of interferon related genes like Ifi203, Ifi202a, Irf1, and Ifit2 (Figure 7).
Negative_regulation (down) of Irf1 in skin associated with targeted disruption
1) Confidence 0.24 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2610035 Disease Relevance 0.85 Pain Relevance 0
Another pathway that was severely affected in skin of K14E6 transgenic mice was the immune response, showing down-regulation of interferon related genes like Ifi203, Ifi202a, Irf1, and Ifit2 (Figure 7).
Negative_regulation (regulation) of Irf1 in skin associated with targeted disruption
2) Confidence 0.24 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2610035 Disease Relevance 0.85 Pain Relevance 0

General Comments

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