INT256923

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Context Info
Confidence 0.11
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.31
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Casp8) peptidase activity (Casp8) mitochondrion (Casp8)
nucleus (Casp8) protein complex (Casp8) cytoplasm (Casp8)
Anatomy Link Frequency
liver 2
Casp8 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 5 72.92 Quite High
Inflammation 13 36.24 Quite Low
cva 5 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Locus ceruleus 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 36 99.76 Very High Very High Very High
Apoptosis 148 97.08 Very High Very High Very High
Targeted Disruption 37 96.16 Very High Very High Very High
Injury 12 89.32 High High
Stress 3 87.04 High High
Hyperplasia 6 61.40 Quite High
Infection 26 60.56 Quite High
Malaria 17 60.16 Quite High
Bites And Stings 2 58.96 Quite High
Papillomavirus Infection 14 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We validated that the expression of Caspase 8, Fas and Birc5 genes was altered by real time RT-PCR (Figure 5).
Regulation (altered) of Gene_expression (expression) of Caspase 8
1) Confidence 0.11 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2610035 Disease Relevance 0.91 Pain Relevance 0
The levels of Fas expression and caspase 8 activities are the same in infected and uninfected liver cells of mice, but hydroxyl radicals are increased in infected mice [36].
Regulation (levels) of Gene_expression (expression) of caspase 8 in liver
2) Confidence 0.04 Published 2010 Journal Parasit Vectors Section Body Doc Link PMC2995786 Disease Relevance 1.40 Pain Relevance 0.04

General Comments

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