INT256935

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.43
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (CCNT1) nucleolus (CCNT1) nucleus (CCNT1)
cell cycle (CCNT1) DNA binding (CCNT1) cell division (CCNT1)
CCNT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
IPN 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 16 98.20 Very High Very High Very High
Adenocarcinoma 1 88.60 High High
Colon Cancer 1 87.16 High High
Targeted Disruption 36 64.12 Quite High
Papillomavirus Infection 14 50.00 Quite Low
Cancer 27 41.84 Quite Low
Influenza Virus Infection 2 21.32 Low Low
Cervical Cancer 9 5.00 Very Low Very Low Very Low
Hyperplasia 5 5.00 Very Low Very Low Very Low
Skin Cancer 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In summary, we identified important genes that are altered at the transcriptional level by E6 in our model, in particular the uncoupling of cell cycle regulation (cdc2, cyclin B, cdk2 and cyclin E), down-regulation of pro-apoptotic genes (Fas) and up-regulation of anti-apoptotic genes (Birc5).
Regulation (regulation) of cyclin B associated with apoptosis
1) Confidence 0.01 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2610035 Disease Relevance 0.43 Pain Relevance 0

General Comments

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