INT25708

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Context Info
Confidence 0.25
First Reported 1989
Last Reported 1989
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 2.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Oprl1, Adra2a) plasma membrane (Oprl1, Adra2a) signal transducer activity (Oprl1, Adra2a)
cytoplasm (Adra2a)
Oprl1 (Mus musculus)
Adra2a (Mus musculus)
Pain Link Frequency Relevance Heat
opiate 5 100.00 Very High Very High Very High
agonist 3 100.00 Very High Very High Very High
intrathecal 2 100.00 Very High Very High Very High
analgesia 1 100.00 Very High Very High Very High
Pain 1 99.44 Very High Very High Very High
antinociception 4 95.44 Very High Very High Very High
Potency 1 91.72 High High
Clonidine 7 90.08 High High
Morphine 10 88.56 High High
narcan 3 81.68 Quite High
Disease Link Frequency Relevance Heat
Pain 1 99.44 Very High Very High Very High
Lumbar Puncture Related Headaches 1 51.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Clinical use of intrathecal combinations of alpha 2 adrenergic and opiate receptor agonists to increase analgesia and use of intrathecal alpha 2 agonists for pain relief in patients tolerant to opiates might deserve evaluation.
opiate receptor Positive_regulation (increase) of alpha 2 associated with pain, agonist, opiate, analgesia and intrathecal
1) Confidence 0.25 Published 1989 Journal Anesth. Analg. Section Abstract Doc Link 2537587 Disease Relevance 0.15 Pain Relevance 2.63

General Comments

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