INT257230

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Nos1) mitochondrion (Nos1) oxidoreductase activity (Nos1)
plasma membrane (Nos1) cytoskeleton (Nos1) nucleus (Nos1)
Anatomy Link Frequency
synapse 1
CALM1 (Homo sapiens)
Nos1 (Mus musculus)
Pain Link Frequency Relevance Heat
nMDA receptor 27 99.12 Very High Very High Very High
Glutamate 7 71.80 Quite High
Central nervous system 15 5.00 Very Low Very Low Very Low
GABAergic 15 5.00 Very Low Very Low Very Low
long-term potentiation 13 5.00 Very Low Very Low Very Low
Serotonin 11 5.00 Very Low Very Low Very Low
depression 11 5.00 Very Low Very Low Very Low
Endocannabinoid 11 5.00 Very Low Very Low Very Low
Neurotransmitter 11 5.00 Very Low Very Low Very Low
Action potential 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 2 19.24 Low Low
Depression 11 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 4 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Ganglion Cysts 3 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 2 5.00 Very Low Very Low Very Low
Demyelinating Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A scenario for efficacious NO generation, therefore, would be in a recently activated synapse where calmodulin with two Ca2+ bound is already associated with nNOS.
calmodulin Binding (associated) of nNOS in synapse
1) Confidence 0.00 Published 2008 Journal The European Journal of Neuroscience Section Body Doc Link PMC2610389 Disease Relevance 0 Pain Relevance 0.15

General Comments

This test has worked.

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